Senior Research Associate I, In Vitro Pharmacology

Keros Therapeutics
April 22, 2024
Lexington, MA
02421

We are seeking a highly motivated Biology/Biochemistry Sr. RA to join our In Vitro Pharmacology team. You will be able to work alongside our team to design and execute in vitro experiments that support preclinical drug discovery, including disease modeling and proof of mechanism validation to characterize our platform candidates. The ideal candidate is a skilled lab-based in vitro biologist driven to contribute to a rigorous scientific environment and a consummate team player. This is a great opportunity to become an integral member of a diverse drug discovery team with ample prospects to progress their career development in drug discovery. Responsibilities: Execute a wide array of experiments in cellular and molecular biology. Perform cell culture routinely; establish and characterize innovative cell lines for disease modeling and pharmacology studies. Develop protocols for diverse assays, meticulously documenting and sharing research findings with colleagues. Actively contribute to the design and troubleshooting of experimental studies, nurturing collaboration with biology teams and cross-functional project groups. Provide essential support for the daily operations of biology labs. Proactively review the literature to bring in the newest scientific findings, ideas, methods, and technologies for discovery research Maintain accurate and detailed laboratory records. Collaborate with team members on multiple research projects. Qualifications: M.S. or B.S. in cell biology or related disciplines. A minimum of 2-5 years of hands-on experience in cellular and molecular biology techniques, including but not limited to flow cytometry, RT-qPCR, western blotting, siRNA/shRNA silencing, CRISPR/CAS9 knockout, plasmid construction and preparation, lentiviral/retroviral transduction, and ELISA-based assays. Proficiency in cell culture techniques, including both immortalized cell lines and primary cells. Previous exposure to organoids or multicellular culture models is highly regarded. Experience in Flow Cytometry is advantageous. Excellent written and verbal communication skills, as well as strong organizational and problem-solving abilities. Enthusiasm for scientific research and a desire to learn and contribute.

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